College of Chemistry

Sickle cell patients such as Cassandra Trimnell and Evie James Junior and UCSF physician Mark Walters talk about the severe pain experienced by those with the disease and the potential benefits of a CRISPR cure. (Video by UC Berkeley Public Affairs; video of Evie Junior by Colin Weatherby, courtesy UCLA’s Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research)

In 2014, two years after her Nobel Prize-winning invention of CRISPR-Cas9 genome editing, Jennifer Doudna thought the technology was mature enough to tackle a cure for a devastating hereditary...

Relaxing with some friends in Shanghai during a meeting. Clockwise direction: Omar Yaghi (back to camera), Osamu Terasaki, Chia-Kuang (Frank) Tsung, Yue-Biao Zhang, Qiaowei Li, Stefan Wuttke, Keinan Ehud, Peidong Yang. Photo courtesy ...

David Schaffer, Hertz Fellow, gene therapy researcher, and The Hubbard Howe Jr. Distinguished Professor of Biochemical Engineering at UC Berkeley says he “plays Darwin” in his Berkeley lab, using high throughput genetic sequencing technology to test over a billion genetic samples for the desired biological activity.

He mutates promising genes and selects...

Plastic is a certainly versatile element. There is much we can do with it. Utensils, tools, parts for cars, technological devices. There is only one thing we do not know how to do with plastic: disappear when it is no longer useful. There the real headache begins and the enormous challenge of obtaining a circular or fully recyclable plastic is posed. Plastics contain various additives, such as dyes, fillers or flame retardants and very few of them can be recycled without loss of performance or aesthetics. The most recyclable plastic, PET (ethylene polyterephthalate), is only recycled at a rate of 20-30%. The rest generally goes to incinerators or landfills where it takes centuries to decompose.