Biochemistry

The race to repurpose nature’s protein factories

February 8, 2021

illustration of ribosomes

The molecular machines that cells use to build proteins are backed by a billion years of evolution. In that time, these machines—ribosomes—have become exceptionally good at forging amide bonds between standard α-amino acids to make peptides and proteins.

Ribosomes are so good at their job that researchers want to harness them to make other polymers...

How scientists shot down cancer’s ‘Death Star’

February 5, 2021

lung cancer cell

A colored scanning electron micrograph of a cell of a common type of lung cancer, called non-small cell cancer. A new drug targets the mutated protein that leads to uncontrolled growth. Credit Steve Gschmeissner/Science Source

After 40 years of effort, researchers have finally succeeded in switching off...

The College of Chemistry celebrates Jennifer Doudna

November 12, 2020

The College of Chemistry was delighted to host an informal discussion with Nobel Laureate, and College faculty member, Jennifer Doudna. Hosted by Dean Douglas Clark and Chair of Chemistry Matthew Francis, Jennifer discussed a wide range of topics from what it was like finding about the award to some really great advice on how to manage your education and career. The session was moderated by graudate students Max Sosa...

New test detects coronavirus in just 5 minutes

November 5, 2020

Jennifer Doudna discusses new COVID-19 test

Jennifer Doudna talks with Alex Ehrenberg, a graduate student in integrative biology who is helping organize the FAST trial of saliva tests for COVID-19. Photo: UC Berkeley/Irene Yi

Researchers have used CRISPR gene-editing technology to come...

UC Berkeley researchers awarded Pew Innovation Funding

September 15, 2020

Ke Xu, Polina

Image: Polina Lishko and Ke Xu (UC Berkeley)

The Pew Charitable Trusts has annouced the 2020 grantees of the Pew Innovation Fund which supports research collaborations among alumni of their...

A behind-the-scenes look at the longevity vitamin PQQ

July 27, 2020

fruit and vegetables

PQQ has been found in fruits and vegetables, such as papaya, kiwi fruit, spinach, green pepper, parsley, celery, and more. Photo: Wen Zhu.

We love food, not only for the joy of eating and sharing meals, but also for the nutrients that our bodies depend on to thrive. Beyond the essential vitamins that everyone needs regularly, scientists have found more...

Professor Richmond Sarpong elected to the American Academy of Arts and Sciences

April 23, 2020

Richmond Sarpong

The College of Chemistry is pleased to announce that Richmond Sarpong, UC Berkeley Professor of Chemistry and Executive Associate Dean of the College of Chemistry, has been named a member of the American Academy of Arts and Sciences. This year, the Academy has elected 276 artists, scholars, scientists, and leaders in the public, non-profit, and private sectors. Sarpong joins fellow members singer Joan Baez and writer Ann Patchett in the 2020 cohort.

The power of change in science

March 9, 2020

women trailblazers

Guided by CRISPR pioneer Jennifer Doudna, a formidable entrepreneur in her own right, C&EN profiled 15 women working in the Chemical industry in academics and startups in C&EN's 2020 Trailblazers. Four of them are affiliated with UC Berkeley's College of Chemistry. They have collectively launched more than 30 start-ups aimed at developing treatments for rare diseases, building better batteries, and more. They’re chemical scientists at the top of their game. They’re role models building and mentoring teams. And yes, they’re badasses. They live by the motto “Nobody ever got anywhere by listening to no.”

Novel synthetic proteins rival their natural counterparts in proton transport

March 3, 2020

polymer membranes

Biological membranes, such as the "walls" of most types of living cells, primarily consist of a double layer of lipids, or "lipid bilayer," that forms the structure, and a variety of embedded and attached proteins with highly specialized functions, including proteins that rapidly and selectively transport ions and molecules in and out of the cell. Scientists have long sought to develop synthetic membranes that could match the selectivity and high-speed transport offered by their natural counterparts. Now a team led by University of California Berkeley researchers has designed a novel polymer that is as effective as natural proteins in transporting protons through a membrane. The results of their research were published in Nature.

Carolyn Bertozzi’s glycorevolution

February 3, 2020

Carolyn Bertozzi’

Carolyn Bertozzi, the glycoscience evangelist has spent her career illuminating the importance of the sugar structures coating our cells. As she turns from building biological tools to building biotech companies, will she see a new wave of converts?