CRISPR Cas9 explained. CRISPR (clustered regularly interspaced short palindromic repeats) are segments of prokaryotic DNA containing short repetitions of base sequences. is an RNA-guided gene-editing platform that makes use of a bacterially derived protein (Cas9) and a synthetic guide RNA to introduce a double strand break at a specific location within the genome.
Cas9 is an enzyme that snips DNA, and CRISPR is a collection of DNA sequences that tells Cas9 exactly where to snip.
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According to a newly published study in Nature, CasX is a potent and efficient gene editor in both bacteria and human cells. Its design is similar to Cas9 and its well-studied cousin, Cas12, but is different enough that it appears to have evolved in bacteria independently of the other Cas proteins. It can cut double-stranded DNA like Cas9, can bind to DNA to regulate genes, and it can be targeted to specific DNA sequences like other Cas proteins.
A breakthrough in genetic technology has given humans more power than ever to change nature. It could help eliminate hunger and disease; it could also lead to the sort of dystopia we used to only read about in sci-fi novels.
Jennifer Doudna, a pioneer of the revolutionary genome-editing technology, reflects on how 2015 became the most intense year of her career — and what she's learned.
Mammoth Biosciences, the biotech startup cofounded by CRISPR researcher Jennifer Doudna, announced today that it has
Dr. Jennifer Doudna has 
The American Cancer Society will bestow its highest honor – the Medal of Honor – to five individuals on Oct. 18 in Washington DC. The Medal of Honor is awarded to distinguished individuals who have made valuable contributions in the fight against cancer. The 2018 recipients include the Honorable Joseph R. Biden Jr., for Cancer Control; Emmanuelle Charpentier, PhD, for Basic Research; Jennifer Doudna, PhD, for Basic Research; Charis Eng, MD, PhD, for Clinical Research; and Michael J. Thun MD, MS, for Cancer Control Science.