Three common pathways of endocytosis in a cell to internalize outside substances. Figure credit: scientificanimations.com, CC BY-SA 4.0, via Wikimedia Commons
Visionary biochemist Jennifer Doudna shared the Nobel Prize last year for the gene-editing technology known as CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), which has the potential to cure diseases caused by genetic mutations. Correspondent David Pogue talks with Doudna about the promises and perils of CRISPR; and with Walter Isaacson, author of the new book "The Code Breaker," about why the biotech revolution will dwarf the digital revolution in importance.
Tuberculosis is caused by Mycobacterium tuberculosis, a bacteria with a cell wall thick enough to block out most drugs. Mireille Kamariza designed a molecule that embeds into that wall and lights up — researchers only need a microscope and a reagent to see it. Photo by Fred Tomlin.
The molecular machines that cells use to build proteins are backed by a billion years of evolution. In that time, these machines—ribosomes—have become exceptionally good at forging amide bonds between standard α-amino acids to make peptides and proteins.
A colored scanning electron micrograph of a cell of a common type of lung cancer, called non-small cell cancer. A new drug targets the mutated protein that leads to uncontrolled growth. Credit Steve Gschmeissner/Science Source
The College salutes the pioneer women chemistry faculty at Cal. Both as scientists, and as early faculty members at the University, they helped to pave the way for the next generations of women faculty and students.
For Nobel Prize winner Jennifer Doudna, the highlight of this most extraordinary Nobel Prize Week was a socially distanced award ceremony on Tuesday, Dec. 8, on her patio in Berkeley with 11 people in attendance, followed by takeout. But if the glow surronding her was any indication, she could have been receiving the medal and citation from the King of Sweden on the stage at Stockholm Concert Hall. The traditional celebration has been rescheduled for next year.
The College salutes the pioneer women chemistry faculty at Cal. Both as scientists, and as early faculty members at the University, they helped to pave the way for the next generations of women faculty and students.