CRISPR gene-editing works to reduce high cholesterol in a new study

November 13, 2025

Gloved hand holding vial

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A single infusion of an experimental gene-editing drug appears safe and effective for cutting cholesterol, possibly for life, according to a small early study released Saturday.

The study, which involved 15 volunteers, found one infusion of a drug that uses the CRISPR gene-editing technique could safely reduce cholesterol, as well as levels of harmful triglycerides, by about half.

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NPR