Biochemistry

The molecular machines that cells use to build proteins are backed by a billion years of evolution. In that time, these machines—ribosomes—have become exceptionally good at forging amide bonds between standard α-amino acids to make peptides and proteins.

Ribosomes are so good at their job that researchers want to harness them to make other polymers...

Jennifer Doudna talks with Alex Ehrenberg, a graduate student in integrative biology who is helping organize the FAST trial of saliva tests for COVID-19. Photo: UC Berkeley/Irene Yi

Researchers have used CRISPR gene-editing technology to come...

Biological membranes, such as the "walls" of most types of living cells, primarily consist of a double layer of lipids, or "lipid bilayer," that forms the structure, and a variety of embedded and attached proteins with highly specialized functions, including proteins that rapidly and selectively transport ions and molecules in and out of the cell. Scientists have long sought to develop synthetic membranes that could match the selectivity and high-speed transport offered by their natural counterparts. Now a team led by University of California Berkeley researchers has designed a novel polymer that is as effective as natural proteins in transporting protons through a membrane. The results of their research were published in Nature.

new research reported from the lab of Markita Landry, a professor of chemical and biomolecular engineering at UC Berkeley, a team of scientists has taken an original approach of using DNA origami nanotechnology to slip through plant cell walls and graft small interfering RNA (siRNA) directly onto plant cells. Their research shows it is possible to directly silence genes in plants without damaging plant tissues, and without making any alterations to the plant’s genome.