Professor of Chemistry
office: 826 Latimer Hall
office phone: 510-642-4488
lab: 915, 916, 917 Latimer Hall
lab phones: 643-1610 (915 Latimer), 642-1609 (917 Latimer)
Organic and Organometallic Chemistry — Natural product total synthesis, Synthetic organic methodology development, Catalyst design.
Synthesis is the unifying theme of our group—total synthesis, new methods for organic synthesis, and the synthesis of new catalyst architectures. In the former area, we are actively pursuing innovative solutions to the total chemical synthesis of a number of complex, biologically active natural products. The identification and realization of powerfully simplifying transformations, which allow for rapid access to the target structure, is a major driving force of our research program. In addition, the interplay between structure and function, and the ability to “re-engineer” natural product structures in an attempt to increase their applicability to problems in biology and medicine is also of particular interest and target selection typically reflects this objective. In a second area, we are interested in exploring unorthodox approaches to catalyst design for transition metal-mediated processes. Traditional metal/ligand catalyst systems often feature rigid ligands with well-defined steric and electronic parameters. We are interested in the synthesis and study of fluxional ligand structures with the potential to access many different steric and electronic states during catalysis. We will use the tools of organic and organometallic chemistry to synthesize and characterize the behavior of these systems.
- Born 1982
- B.S. University of California, Berkeley (2004)
- Ph.D. The Scripps Research Institute (2009)
- NIH Postdoctoral Fellow, Massachusetts Institute of Technology (2009-2012)
- Elsevier Reaxys Prize (2010)
- Roche Excellence in Chemistry Award (2008)
- ACS Division of Organic Chemistry Graduate Fellowship (2008)
- Bristol-Myers Squibb Graduate Fellowship (2007)
- Erich O. & Elly M. Saegebarth Prize in Chemistry (2004)