CRISPR

CRISPR Cas9 explained. CRISPR (clustered regularly interspaced short palindromic repeats) are segments of prokaryotic DNA containing short repetitions of base sequences. is an RNA-guided gene-editing platform that makes use of a bacterially derived protein (Cas9) and a synthetic guide RNA to introduce a double strand break at a specific location within the genome.

Cas9 is an enzyme that snips DNA, and CRISPR is a collection of DNA sequences that tells Cas9 exactly where to snip.

National Academy of Sciences honors Raghavendra, Doudna

January 17, 2018

Jennifer DoudnaPrasad Raghavendra, an associate professor of electrical engineering and computer science, and Jennifer Doudna, a professor of molecular and cell biology and of chemistry, were honored this week by the National Academy of Sciences for their innovative body of research.

First step toward CRISPR cure of Lou Gehrig's disease

December 20, 2017

David SchafferDavid Schaffer and fellow UC Berkeley scientists have for the first time used CRISPR-Cas9 gene editing to disable a defective gene that causes amyotrophic lateral sclerosis, or Lou Gehrig's disease, in mice, extending their lifespan by 25 percent.

Book Club: A Crack in Creation

October 19, 2017

A Crack in CreationPodcast on the development of Crispr, and the ethical questions raised by new genome editing techniques.

Doudna awarded Japan Prize for invention of CRISPR gene editing

February 2, 2017

Emmanuelle Charpentier, Jennifer Doudna receiving 2017 Japan PrizeJennifer Doudna and Emmanuelle Charpentier were awarded the Japan Prize today for their invention of the revolutionary gene-editing technology known as CRISPR-Cas9, which has swept into research labs around the world and is already yielding new therapies for cancer and hereditary diseases.

White House summit advances the ‘cancer moonshot’

June 29, 2016

Jennifer DoudnaThe cancer moonshot aims to end cancer as it is known today. One of the key discoveries in that effort is CRISPR/Cas9 pioneered by Jennifer Doudna.

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