CRISPR Cas9 explained. CRISPR (clustered regularly interspaced short palindromic repeats) are segments of prokaryotic DNA containing short repetitions of base sequences. is an RNA-guided gene-editing platform that makes use of a bacterially derived protein (Cas9) and a synthetic guide RNA to introduce a double strand break at a specific location within the genome.
Cas9 is an enzyme that snips DNA, and CRISPR is a collection of DNA sequences that tells Cas9 exactly where to snip.
Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9. The work benefited from input from Professor Jennifer Doudna.
The Washing Post interviews Jennifer Doudna on the heated ethical and legal debates triggered by the discovery of CRISPR.
Jennifer Doudna shares 2016 Canada Gairdner International Awards with four others for discovering and re-engineering the CRISPR-Cas9 system.
Jennifer Doudna on the ethical and societal issues of editing heritable genes.
A new study from UC Berkeley illustrates the ease with which CRISPR-Cas9 can knock out genes in exotic animals — in this case, an amphipod or sandhopper — to learn how those genes control growth and development.- « first View: Taxonomy term
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