CRISPR

CRISPR Cas9 explained. CRISPR (clustered regularly interspaced short palindromic repeats) are segments of prokaryotic DNA containing short repetitions of base sequences. is an RNA-guided gene-editing platform that makes use of a bacterially derived protein (Cas9) and a synthetic guide RNA to introduce a double strand break at a specific location within the genome.

Cas9 is an enzyme that snips DNA, and CRISPR is a collection of DNA sequences that tells Cas9 exactly where to snip.

Book Club: A Crack in Creation

October 19, 2017

A Crack in CreationPodcast on the development of Crispr, and the ethical questions raised by new genome editing techniques.

Doudna awarded Japan Prize for invention of CRISPR gene editing

February 2, 2017

Emmanuelle Charpentier, Jennifer Doudna receiving 2017 Japan PrizeJennifer Doudna and Emmanuelle Charpentier were awarded the Japan Prize today for their invention of the revolutionary gene-editing technology known as CRISPR-Cas9, which has swept into research labs around the world and is already yielding new therapies for cancer and hereditary diseases.

White House summit advances the ‘cancer moonshot’

June 29, 2016

Jennifer DoudnaThe cancer moonshot aims to end cancer as it is known today. One of the key discoveries in that effort is CRISPR/Cas9 pioneered by Jennifer Doudna.

Read the article.

Doudna joins Biden in Davos rollout of ‘cancer moonshot’

January 19, 2016

Doudna at World Economic ForumJennifer Doudna joined Joseph Biden this morning at the World Economic Forum in Davos, Switzerland, as the vice president promoted a major new U.S. initiative to speed the discovery of cures for cancer, what President Obama has dubbed a "cancer moonshot."...

Taiwan’s Tang Prizes awarded to Doudna, Rosenfeld

June 20, 2016

Jennifer DoudnaTaiwan's top science award, the Tang Prize, has gone to two UC Berkeley scientists well-known in the fields of biochemistry and physics: Jennifer Doudna, for her invention of CRISPR-Cas9 gene editing, and Arthur Rosenfeld, often called the "godfather of energy efficiency."

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CRISPR-Gold fixes Duchenne muscular dystrophy mutation in mice

October 3, 2017

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease.