College of Chemistry

On the brink of his 100th trip around the sun, the secret to David Altman’s (Ph.D. '43, Chem) long and illustrious life isn’t rocket science. At least, not entirely. It’s a strategy that seems to have worked well for Altman, who will officially become a centenarian on Thursday. His dizzying number of accomplishments in rocket science — papers written, patents held, awards won — seem to indicate that not a moment was wasted in all of his one hundred years.

Carolyn Bertozzi, the glycoscience evangelist has spent her career illuminating the importance of the sugar structures coating our cells. As she turns from building biological tools to building biotech companies, will she see a new wave of converts?

One of biology’s wilder facts is that we’re all family. You and me, sure, but also me and a mushroom. Triceratops shared genes with you. So does the virus that makes you cough, and a rosebush. Bacteria left us on the tree of life around 2.7 billion years ago, but the wet world they came from is still ours: One code runs all of life. The same proteins that imprint memories in your neurons, for example, do so in octopi, ravens, and sea slugs. This genetic conservation means tricks from one species can be hijacked. If you stick a jellyfish gene in a monkey, it’ll glow green.

Protein-like molecules called “polypeptoids” (or “peptoids,” for short) have great promise as precision building blocks for creating a variety of designer nanomaterials, like flexible nanosheets – ultrathin, atomic-scale 2D materials. They could advance a number of applications – such as synthetic, disease-specific antibodies and self-repairing membranes or tissue – at a low cost.Scientists at Berkeley Lab are the first to use cryogenic electron microscopy (cryo-EM) to image atomic changes in artificial proteins known as “peptoids.” Their findings have implications for the synthesis of soft, 2D materials for a wide variety of applications.