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Student Information: Course Information: Department of Chemistry Courses

Chemistry Course Offerings
Lower division courses
Upper division courses
Graduate courses
Professional courses

Other Course Offerings
Chemical Engineering courses
UC Berkeley online schedule of classes

Lower Division Courses spacer image Class Description
Chemistry 1A
General Chemistry. (4) Students will receive no credit for 1A after taking 4A. Three hours of lecture and four hours of laboratory per week. Prerequisite: High school chemistry recommended. Stoichiometry of chemical reactions, quantum mehanical description of atoms, the elements and the periodic table, chemical bonding, real and ideal gases, thermochemistry, introduction to thermodynamics and equilibrium, acid-base and solubility equilibria, introduction to oxidation-reduction reactions. (F, S)
 
General Chemistry. (4) Course 4B will restrict credit if completed before 1B. Two hours of lecture and four hours of laboratory per week. Prerequisite: 1A or a score of 3, 4, or 5 on the Chemistry AP test. Introduction to chemical kinetics, electrochemistry, properties of the states of matter, binary mixtures, thermodynamic efficiency and the direction of chemical change, quantum mechanical description of bonding, introduction to spectroscopy. Special topics: Research topics in modern chemistry and biochemistry, chemical engineering. (S)
 
Chemical Structure and Reactivity. (3)Course 112A will restrict credit if completed prior to 3A. Three hours of lecture per week. Prerequisite: 1A with a grade of C- or higher, or a score of 4 or 5 on the Chemistry AP test. Concurrent enrollment in 3AL required. Introduction to organic chemical structures, bonding, and chemical reactivity. The organic chemistry of alkanes, alkyl halides, alcohols, alkenes, alkynes, and organometallics. (F, S)
Chemistry 3AL
 
Organic Chemistry Laboratory. (2) Course 112A will restrict credit if completed prior to 3AL. One hour of lecture and four hours of laboratory per week. Prerequisite: 1A with a grade of C- or higher, or a score of 4 or 5 on the Chemistry AP test. Must be taken concurrently with 3A. Introduction to the theory and practice of methods used in the organic chemistry laboratory. An emphasis is placed on the separation and purification of organic compounds. Techniques covered will include extraction, distillation, sublimation, recrystallization, and chromatography. Detailed discussions and applications of infrared and nuclear magnetic resonance spectroscopy will be included. (F, S)
 
Chemical Structure and Reactivity. Course 112B will restrict credit if completed prior to 3B. Three hours of lecture per week. Prerequisite: 3A with a grade of C- or better. Conjugation, aromatic chemistry, carbonyl compounds, carbohydrates, amines, carboxylic acids, amino acids, peptides, proteins, and nucleic acid chemistry. Ultraviolet spectroscopy and mass spectrometry will be introduced. (F, S)
Chemistry 3BL   Organic Chemistry Laboratory. (2) Course 112B will restrict credit if completed prior to 3BL. One hour of lecture and four hours of laboratory per week. Prerequisites: 3AL; 3B (may be taken concurrently). The synthesis and purification of organic compounds will be explored. Natural product chemistry will be introduced. Advanced spectroscopic methods including infrared, ultraviolet, and nuclear magnetic resonance spectroscopy and mass spectrometry will be used to analyze products prepared and/or isolated. Qualitative analysis of organic ompounds will be covered. (F, S)
 
General Chemistry and Quantitative Analysis. (4;4) Courses 1A or 1B will restrict credit if completed prior to 4A-4B. Three hours of lecture and four hours of laboratory
per week. Prerequisites: High school chemistry; calculus (may be taken concurrently);
high school physics is recommended. The series 4A-4B is intended for majors in
engineering and physical and biological sciences. It presents the foundation principles of
chemistry, including stoichiometry, ideal and real gases, acid-base and solubility equilibria,
oxidation-reduction reactions, thermochemistry, entropy, nuclear chemistry and radioactivity, the atoms and elements, the periodic table, quantum theory, chemical bonding, molecular structure, chemical kinetics, and descriptive chemistry. Examples and applications will be drawn from diverse areas of special interest such as atmospheric, environmental, materials, polymer and computational chemistry and biochemistry. Laboratory emphasizes quantitative work. 4A (F); 4B (S)
Chemistry 10
 
Chemical Attractions. (3) For nonscience majors. Three hours of lecture and one hour of discussion per week. The principles of chemistry permeate everything in the world around us. From the protection of sunscreens and the seductiveness of perfumes to the processes of DNA fingerprinting and art restoration to the foods and pharmaceuticals we ingest, chemistry is a crucial player in improving the quality of our lives. This course will introduce the nonscience major to chemical principles by exploring various “themes” such as perfumes and chemical communication, pesticides and the environment, diet and exercise, drugs and blood chemistry, art restoration, criminology, and plastics. In lieu of traditional problem sets and laboratories common in chemistry courses, students will prepare critiques of science as it is presented in the media, participate in solving a mock crime, and stage debates about the risks and benefits of chemistry. The course will culminate with group projects whereby students pursue a question or “theme” of their own interest.
Chemistry 24
 
Freshman Seminar. (1) Course may be repeated for credit as topic varies. One hour of
seminar per week. Sections 1-2 to be graded on a letter-grade basis. Sections 3-4 to be
graded on a passed/not passed basis. The Freshman Seminar Program has been designed
to provide new students with the opportunity to explore an intellectual topic with a faculty
member in a small-seminar setting. Freshman seminars are offered in all campus departments, and topics may vary from department to department and semester to semester. Enrollment is limited to 15 freshmen. (F)
Chemistry 49
 
Supplementary Work in Lower Division Chemistry. (1-4) Course may be repeated for credit. Meetings to be arranged. Students with partial credit in lower division Chemistry courses may, with consent of instructor, complete the credit under this heading.
Chemistry 84
 
Sophomore Seminar. (1-2) One hour of seminar per week per unit for fifteen weeks.
One and one half hours of seminar per week per unit for 10 weeks. Two hours of seminar
per week per unit for eight weeks. Three hours of seminar per week per unit for five weeks.
Sections 1–2 to be graded on a passed/not passed basis. Sections 3–4 to be graded on a
letter-grade basis. Prerequisites: At discretion of instructor. Sophomore seminars are small
interactive courses offered by faculty members in departments all across the campus.
Sophomore seminars offer opportunity for close, regular intellectual contact between
faculty members and students in the crucial second year. The topics vary from department
to department and semester to semester. Enrollment limited to 15 sophomores. May be
repeated for credit as topic varies.
Chemistry C96
 
Introduction to Research and Study in the College of Chemistry. (1) One hour of seminar per week. Must be taken on a passed/ not passed basis. Prerequisites: Freshman 31 standing in chemistry, chemical biology, or chemical engineering major, or consent of instructor. Chemistry and chemical biology majors enroll in Chemistry C96 and chemical engineering majors enroll in Chemical Engineering C96. Introduces freshmen to research activities and programs of study in the College of Chemistry. Includes lectures by faculty, an introduction to college library and computer facilities, the opportunity to meet alumni and advanced undergraduates in an informal atmosphere, and discussion of college and campus resources. Also listed as Chemical Engineering C96. (F)
Chemistry 98
 
Supervised Group Study. (1-4) Enrollment is restricted; see the “Introduction to Courses and Curricula” section of the General Catalog. One hour of work per week per unit. Must be taken on a passed/not passed basis. Prerequisite: Consent of instructor. Group study of selected topics.
 
Issues in Chemistry. (1) Course may be repeated for credit as topic varies. One hour
of seminar per week. Must be taken on a passed/not passed basis. Prerequisite: Score
of 3, 4 or 5 on the Chemistry AP test, or 1A or 4A (may be taken concurrently). This seminar
will focus on one or several related issues in society that have a significant chemical
component. Particular topics will differ between sections of the course and from year
to year. Representative examples: atmospheric ozone, nuclear waste, solar energy, water,
agrichemicals. Students will search information sources, invite expert specialists, and
prepare oral and written reports.
Chemistry 98W
 
Directed Group Study. (1) Course may be repeated for credit. Must be taken on a
passed/not passed basis. Topics vary with instructor. Enrollment restrictions apply. (F, S)
Upper Division Courses spacer image Class Description
Chemistry 100
 
Communicating Chemistry. (2) Formerly 20. Course may be repeated for credit. Two hours of lecture and one hour of fieldwork per week. For undergraduate and graduate students interested in improving their ability to communicate their scientific knowledge by teaching chemistry in elementary schools. The course will combine instruction in inquiry-based chemistry teaching methods and learning pedagogy with 10 weeks of supervised teaching experience in a local school classroom. Thus, students will practice communicating scientific knowledge and receive mentoring on how to improve their presentations. Approximately three hours per week, including time spent in school classrooms. (S)
Chemistry 103
 
Inorganic Chemistry in Living Systems. (3) Courses 104A or 104B will restrict credit if completed before 103. Three hours of lecture per week. Prerequisite: 4B or 1B. The basic principles of metal ions and coordination chemistry applied to the study of biological systems. (F)
Chemistry 104A
Chemistry 104B
 
Advanced Inorganic Chemistry. (3;3) Course 103 will restrict credit if completed before 104A. Three hours of lecture per week. Prerequisites 104A: 1B, 4B, or 3A; 104B: 104A or consent of instructor. The chemistry of metals and nonmetals including the application of physical chemical principles. 104A (F); 104B (S)
Chemistry 105
 
Instrumental Methods in Analytical Chemistry. (4) Two hours of lecture and two 4- hour laboratories per week. Prerequisite: 4B. Principles, instrumentation, and analytical
applications of atomic spectroscopies, mass spectrometry, separations, electrochemistry,
and micro-characterization. Discussion of instrument design and capabilities as well as
real-world problem solving with an emphasis on bioanalytical, environmental, and forensic
applications. Hands-on laboratory work using modern instrumentation, emphasizing independent projects involving real-life samples and problem solving. (F, S)
Chemistry 108
 
Inorganic Synthesis and Reactions. (4) Two hours of lecture and eight hours of laboratory
per week. Prerequisites: 4B; 104A with a grade of C- or higher; 104B (may be taken
concurrently). The preparation of inorganic compounds using vacuum line, air- and moisture-
exclusion, electrochemical,high-pressure, and other synthetic techniques. Kinetic and mechanistic studies of inorganic compounds. (F, S)

Chemistry 112A
Chemistry 112B

 
Organic Chemistry. (5;5) Courses 3A, 3AL, 3B or 3BL will restrict credit if
completed prior to 112A-112B. Three hours of lecture, one hour of laboratory lecture, and five
hours of laboratory per week. Prerequisite: 112A: 1B or 4B with a grade of C- or higher.
112B: 112A with a grade of C- or higher. For students majoring in chemistry, chemical biology,
or a closely related field such as chemical engineering or molecular and cell biology. A
study of all aspects of fundamental organic chemistry, including nomenclature, chemical
and physical properties, reactions and syntheses of the major classes of organic compounds.
The study includes theoretical aspects, reaction mechanisms, multistep syntheses and the
chemistry of polycyclic and heterocyclic compounds. This course is more extensive and
intensive than 3A-3B and includes a greater emphasis on reaction mechanisms and multistep
syntheses. 112A (F); 112B (S)
Chemistry 113
 
Advanced Mechanistic Organic Chemistry. (3) Three hours of lecture per
week. Prerequisite: 3B or 112B with a minimum grade of B-, or consent of instructor.
Advanced topics in mechanistic and physical organic chemistry, typically including kinetics,
reactive intermediates, substitution reactions, linear free energy relationships, orbital interactions and orbital symmetry control of reactions, isotope effects, and photochemistry. (F)
Chemistry 114
 
Advanced Synthetic Organic Chemistry. (3) Three hours of lecture per week. Prerequisite: 3B or 112B with a minimum grade of B-, or consent of instructor. Advanced topics in synthetic organic chemistry with a focus on selectivity. Topics include reductions, oxidations, enolate chemistry and the aldol reaction, reactions of nonstabilized anions, olefination reactions, pericyclic reactions, and application to the synthesis of complex structures. (S)
 
Organic Chemistry—Advanced Laboratory Methods. (4) One hour of lecture and 11 hours of laboratory per week. Prerequisite: 112B with a grade of C- or higher. Advanced synthetic methods, chemical and spectroscopic structural methods, designed as a preparation for experimental research. (F, S)
 
Physical Chemistry. (3) Course 130B will restrict credit if completed before 120A. Three hours of lecture per week. Prerequisites: 4B or equivalent; Math 53; Physics 7B or 8B;
Math 54 (may be taken concurrently). Kinetic, potential, and total energy of particles and
forces between them; principles of quantum theory, including one-electron and manyelectron
atoms. The course will be divided (fall semester) into a section for chemistry majors
and one for chemical biology majors, both meeting at the same time, covering topics of
interest to each group relating to molecules and chemical bonding, electrical properties,
intermolecular interactions, and elementary spectroscopy. (F, S)
Chemistry 120B
 
Physical Chemistry. (3) Courses C130 or MCB C100A will restrict credit if completed
before 120B. Three hours of lecture per week. Prerequisites: 4B or equivalent;
Math 53; Physics 7B or 8B; Math 54 (may be taken concurrently). Statistical mechanics,
thermodynamics, and equilibrium. The course will be divided (spring semester) into a section
for chemistry majors and one for chemical biology majors, both meeting at the same
time, covering topics of interest to each group relating to states of matter, solutions and
solvation, (bio)chemical kinetics, molecular dynamics, physical characterization, and transport of molecules. (F, S)
Chemistry 122
 
Quantum Mechanics and Spectroscopy. (3) Three hours of lecture per week. Prerequisite: 120A. Postulates and methods of quantum mechanics and group theory applied to molecular structure and spectra.
Chemistry 125
 
Physical Chemistry Laboratory. (3) Course C182 and Earth and Planetary Science C182 might restrict credit if completed before 125. Instructor’s approval is required to enroll in 125 after completing C182. One hour of lecture and one 5-hour laboratory per week. Prerequisites: Two of 120A, 120B, 130A, or 130B with grades of C- or higher (one of which may be taken concurrently). Experiments in thermodynamics, kinetics, molecular structure, and general physical chemistry. (F, S)
 
Biophysical Chemistry: Physical Principles and the Molecules of Life. (4) Course 120B will restrict credit if completed before C130/MCB C100A. Three hours of lecture and one hour of discussion per week. Prerequisites: Math 1A; Biology 1A; Chemistry 3A or 112A; Chemistry 3B or 112B recommended. Thermodynamic and kinetic concepts applied to understanding the chemistry and structure of biomolecules (proteins, DNA, and RNA). Molecular distributions, reaction kinetics, enzyme kinetics. Bioenergetics, energy transduction, and motor proteins. Electrochemical potential, membranes, and ion channels. Also listed as MCB C100A. (F, S)
Chemistry 135
 
Biophysical Chemistry. (3) Courses 120A and 120B will restrict credit if completed prior to 130B. Two hours of lecture and one hour of discussion per week. Prerequisite: 130A or consent of instructor. The weekly onehour discussion is for problem solving and the application of calculus in physical chemistry. Molecular structure, intermolecular forces and
interactions, biomolecular spectroscopy, highresolution structure determinations. (S)
Chemistry 143
 
Nuclear Chemistry. (2) Two hours of lecture per week. Prerequisite: Physics 7B or equivalent. Radioactivity, fission, nuclear models and reactions, nuclear processes in nature. Computer methods will be introduced. (F)
Chemistry 146
 
Chemical Methods in Nuclear Technology. (3) Formerly 144. One 11/2-hour lecture and one 41/2-hour laboratory per week. Prerequisites: 4B; 143 is recommended. Experimental illustrations of the interrelation between chemical and nuclear science and technology; fission process, chemistry of fission fragments, chemical effects of nuclear transformation; application of radioactivity to study of chemical problems; neutron activation analysis. (S)
Chemistry C150
 
Introduction to Materials Chemistry. (3) Three hours of lecture per week. Prerequisite: 104B is recommended. The application of basic chemical principles to problems in materials discovery, design, and characterization will be discussed. Topics covered will include inorganic solids, nanoscale materials, polymers, and biological materials, with specific focus on the ways in which atomic-level interactions dictate the bulk properties of matter. Also listed as Materials Science and Engineering C150. (S)
Chemistry 170L
 
Biochemical Engineering Laboratory. (3) One hour of lecture and six hours of laboratory per week. Prerequisite: Chemical Engineering 170 (may be taken concurrently) or consent of instructor. Laboratory techniques for the cultivation of microorganisms in batch and continuous reactions. Enzymatic conversion processes. Recovery of biological products. Also listed as Chemical Engineering C170L. (S)
Chemistry 178
 
Polymer Science and Technology. (3) Three hours of lecture/laboratory per week. Prerequisites: One semester of organic chemistry and physics recommended; Chemical
Engineering 150A, equivalent fluid mechanics, or consent of instructor. Introduction to physirequisites cal and chemical behavior of organic polymers. Properties of solutions, melts, glasses, elastomers, and crystals. Engineering applications emphasizing processing technology. Experiments in polymerization and characterization. Also listed as Chemical Engineering C178. (F)
Chemistry 182
 
Atmospheric Chemistry and Physics Laboratory. (3) Course 125 might restrict
credit if completed before C182. Instructor’s approval is required to enroll in C182 after
completing 125. One hour of lecture and five hours of laboratory per week. Prerequisites:
College-level calculus, chemistry and physics, or consent of instructor. Fluid dynamics,
radiative transfer, and the kinetics, spectroscopy, and measurement of atmospherically
relevant species are explored through laboratory experiments, numerical simulations, and
field observations. The course is intended for Earth and Planetary Science majors and minors,
and for chemistry, physics, astronomy, biology, and engineering majors whose interests may lie in science applied to the atmosphere of Earth and other planets. Also listed as Earth and
Planetary Science C182.
 
Quantum Information Science and Technology. (3) Three hours of lecture and one hour of discussion per week. Prerequisites: Math 54; Physics 7A; Physics 7B; and either Physics 7C, Math 55, or Computer Science 170 are required. This multidisciplinary course provides an introduction to fundamental conceptual aspects of quantum mechanics from a computational and informational theoretic perspective, as well as physical implementations and technological applications of quantum information science. Basic sections of quantum algorithms, complexity, and cryptography will be touched upon, as well as pertinent physical realizations from nanoscale science and engineering. Also listed as Computer Science C191 and Physics C191. (F)
Chemistry 192
 
Individual Study for Advanced Undergraduates. (1-3) Course may be repeated for
credit. Individual conferences. Prerequisites: Consent of instructor and adviser. All properly
qualified students who wish to pursue a problem of their own choice, through reading or
nonlaboratory study, may do so if their proposed project is acceptable to the member of
the staff with whom they wish to work. (F, S)
Chemistry H194
 
Research for Advanced Undergraduates. (2-4) Course may be repeated for credit. Minimum of three hours of work per week per unit of credit. Prerequisites: Minimum GPA of 3.4 overall at Berkeley and consent of instructor and adviser. Students may pursue original research under the direction of one of the members of the staff. (F, S)
Chemistry 195
 
Special Topics. (3) Course may be repeated for credit. Three hours of lecture per week. Prerequisite: Consent of instructor. Special topics will be offered from time to time. Examples are photochemical air pollution, computers in chemistry.
Chemistry 196
 
Special Laboratory Study. (2-4) Course may be repeated for credit. Laboratory. prerequisites:
Consent of instructor and adviser. Special laboratory work for advanced undergraduates. (F, S)
Chemistry 198  
Directed Group Study. (1-4) One hour of class per week per unit. Course may be repeated for credit. Must be taken on a passed/not passed basis. Prerequisites: Completion of 60 units of undergraduate study and in good academic standing. Group study of selected topics. Enrollment is restricted; see the Introduction to Courses and Curricula section of the General Catalog.
Chemistry 199
 
Supervised Independent Study and Research. (1-4) Course may be repeated for credit. Must be taken on a passed/not passed basis. Nonlaboratory study only. Enrollment is restricted by regulations listed in the General Catalog. (F, S)
Graduate Courses
 
Class Description
Chemistry 200
 
Chemistry Fundamentals. (1) Three hours of lecture per week for five weeks. Prerequisite: Graduate standing or consent of instructor. Review of bonding, structure, stereochemistry,
conformation, thermodynamics and kinetics, and arrow-pushing formalisms. (F)
Chemistry 201
 
Fundamentals of Inorganic Chemistry. (1) Three hours of lecture per week for five weeks. Prerequisite: Graduate standing or consent of instructor. Review of bonding, structure, MO theory, thermodynamics, and kinetics. (F)
Chemistry 208
 
Structure Analysis by X-Ray Diffraction. (4) Two 1-hour lectures and two 4-hour laboratories per week. Prerequisite: Consent of instructor. The theory and practice of modern, single-crystal X-ray diffraction. Groups of four students determine the crystal and molecular structure of newly synthesized materials from the College of Chemistry. The laboratory work involves the mounting of crystals and initial evaluation by X-ray diffraction film techniques, the collection of intensity data by automated diffractometer procedures, and structure analysis and refinement. (S)
Chemistry 220A
 
Thermodynamics and Statistical Mechanics. (3) Three 1-hour lectures per week. Prerequisite: 120B. A rigorous presentation of classical thermodynamics followed by an introduction to statistical mechanics with the application to real systems. (F)
Chemistry 220B
 
Statistical Mechanics. (3) Three 1- hour lectures per week. Prerequisite: 220A. Principles of statistical mechanics and applications to complex systems. (S)
Chemistry 221A
 
Advanced Quantum Mechanics. (3) Three hours of lecture per week. Prerequisites: 120B and 122 or equivalent. Introduction, one dimensional problems, matrix mechanics, approximation methods. (F)
Chemistry 221B
 
Advanced Quantum Mechanics. (3) Three hours of lecture per week. Prerequisite: 221A. Time dependence, interaction of matter with radiation, scattering theory. Molecular and many-body quantum mechanics. (S)
Chemistry 223A
 
Chemical Kinetics. (3) Three hours of lecture per week. Prerequisite: 220A (may be taken concurrently). Deduction of mechanisms of complex reactions. Collision and transition state theory. Potential energy surfaces. Unimolecular reaction rate theory. Molecular beam scattering studies. (S)
Chemistry 223B
 
Chemical Dynamics. (3) Three hours of lecture per week. Prerequisites: 221A, 223A. Quantum mechanical scattering theory of elastic, inelastic, and reactive collisions. Electronically non-adiabatic processes. Collision complexes and scattering resonances. Semiclassical scattering theory for molecular collision. Generalized statistical models for chemical reactions. (F)
Chemistry 230
 
Protein Chemistry, Enzymology, and Bio-organic Chemistry. (3) Three hours of lecture per week. Prerequisite: Graduate standing or consent of instructor. The topics covered will be chosen from the following: protein structure, denaturation, and folding; RNA catalysis; protein-protein and proteinnucleic acid interactions; enzyme kinetics and mechanism; catalytic antibodies. Intended for graduate students in chemistry, biochemistry, and molecular and cell biology. Also listed as MCB C214.
Chemistry 243
 
Advanced Nuclear Structure and Reactions. (3) Three hours of lecture per week. Prerequisites: 143 or equivalent and introductory quantum mechanics. Selected topics on nuclear structure and nuclear reactions.
Chemistry 250A
 
Introduction to Bonding Theory. (1) Three hours of lecture per week for five weeks. Prerequisites: 200 or 201 or consent of instructor and background in the use of matrices and linear algebra. An introduction to group theory, symmetry, and representations as applied to chemical bonding. (F)
Chemistry 250B
 
Inorganic Spectroscopy. (1) Three hours of lecture per week for five weeks. Prerequisite: 250A or consent of instructor. The theory of vibrational analysis and spectroscopy as applied
to inorganic compounds. (S)
Chemistry 251A
 
Coordination Chemistry I. (1) Three hours of lecture per week for five weeks. Prerequisite: 250A or consent of instructor. Structure and bonding, synthesis, and reactions of the d-transition metals and their compounds. (F)
Chemistry 251B
 
Coordination Chemistry II. (1) Three hours of lecture per week for five weeks. Prerequisite: 251A or consent of instructor. Synthesis, structure analysis, and reactivity patterns in terms of symmetry orbitals.
Chemistry 252A
 
Organometallic Chemistry I. (1) Three hours of lecture per week for five weeks. Prerequisite: 200 or 201 or consent of instructor. An introduction to organometallics, focusing on structure, bonding, and reactivity. (F)
Chemistry 252B
 
Organometallic Chemistry II. (1) Three hours of lecture per week for five weeks. Prerequisite: 252A or consent of instructor. Applications of organometallic compounds in synthesis with an emphasis on catalysis. (F)
Chemistry 253A
 
Materials Chemistry I. (1) Three hours of lecture per week for five weeks. Prerequisites: 200 or 201, and 250A, or consent of instructor. Introduction to the descriptive crystal chemistry and electronic band structures of extended solids.
Chemistry 253A
 
Materials Chemistry II. (1) Three hours of lecture per week for five weeks. Prerequisite: 253A or consent of instructor. General solid-state synthesis and characterization techniques as well as a survey of important physical phenomena including optical, electrical, and magnetic properties.
Chemistry 253B
 
Materials Chemistry II. (1) Three hours of lecture per week for five weeks. Prerequisite: 253A or consent of instructor. General solid-state synthesis and characterization techniques as well as a survey of important physical phenomena including optical, electrical, and magnetic properties.
Chemistry 253C
 
Materials Chemistry III. (1) Three hours of lecture per week for five weeks. Prerequisite: 253A or consent of instructor. Introduction to surface, catalysis, organic solids, nanoscience. Thermodynamics and kinetics of solid
Chemistry 254
 
Bioinorganic Chemistry. (1) Three hours of lecture per week for five weeks. A survey of the roles of metals in biology, taught as a tutorial involving class presentations. (S)
Chemistry 256
 
Electrochemical Methods. (1) Three hours of lecture per week for five weeks. The effect of structure and kinetics on the appearance of cyclic voltammograms and the use of cyclic voltammetry to probe the thermodynamics, kinetics, and mechanisms of electrochemical reactions.
Chemistry 260
 
Reaction Mechanisms. (2) Formerly 260A-260B. Three hours of lecture and inclass discussion and problem solving for 10 weeks and one week of computer laboratory. Prerequisite: 200 or 201 or consent of instructor. Advanced methods for studying organic reaction mechanisms. Topics include kinetic isotope effects, behavior of reactive intermediates, chain reactions, concerted reactions, molecular orbital theory and aromaticity, solvent and substituent effects, linear free energy relationships, photochemistry. (F)
Chemistry 261A
 
Organic Reactions I. (1) Three hours of lecture per week for five weeks. Prerequisite: 200 or 201 or consent of instructor. Features of the reactions that comprise the vocabulary of synthetic organic chemistry. (F)
Chemistry 261B
 
Organic Reactions II. (1) Three hours of lecture per week for five weeks. Prerequisite: 261A or consent of instructor. More reactions that are useful to the practice of synthetic organic chemistry. (F)
Chemistry 261C
 
Organic Reactions III. (1) Three hours of lecture per week for five weeks. Prerequisite: 261B or consent of instructor. This course will consider further reactions with an emphasis on pericyclic reactions such as cycloadditions, electrocyclizations, and sigmatropic arrangements. (F)
Chemistry 262
 
Metals in Organic Synthesis. (1) Three hours of lecture per week for five weeks. Prerequisite: 261B or consent of instructor. Transition metal-mediated reactions occupy a central role in asymmetric catalysis and the synthesis of complex molecules. This course will describe the general principles of transition metal reactivity, coordination chemistry, and stereoselection. This module will also emphasize useful methods for the analysis of these reactions. (S)
Chemistry 263A
 
Synthetic Design I. (1) Three hours of lecture per week for five weeks. Prerequisite: 262 or consent of instructor. This course will describe the application of modern reactions to the total synthesis of complex target molecules. Natural products, such as alkaloids, terpenes, or polypropionates, as well as theoretically interesting “non-natural” molecules will be covered. (S)
Chemistry 263B
 
Synthetic Design II. (1) Three hours of lecture per week for five weeks. Prerequisite: 263A or consent of instructor. The principles of retrosynthetic analysis will be laid down and the chemistry of protecting groups will be discussed. Special attention will be given to the automated synthesis of biopolymers such as carbohydrates, peptides, and proteins, as well as nucleic acids.
Chemistry 264A   Synthesis of Macromolecules. (1) Three hours of lecture per week for five weeks. rerequisite: 200 or consent of instructor. The concepts of chain-growth and step-growth polymerizations. Radical, ionic, and metal catalyzed polymerizations. Living polymerization. Controlling macromolecular architecture: dendrimers, hyperbranced polymers, and crosslinked networks.
Chemistry 264B   Properties and Applications of Macromolecules. (1) Three hours of lecture per week for five weeks. Prerequisite: 264A or consent of instructor. Characterization of macromolecules. Structure-property relationships. Specialty polymers and their applications: polymers in therapeutics, biomedical polymers and implants, conducting polymers, polymers in microelectronics and photonics, polymers in separation and molecular recognition, supramolecular chemistry, and self-assembly.
Chemistry 265   Nuclear Magnetic Resonance Theory and Application. (1) Three hours of lecture per week for five weeks. Prerequisite: 200 or 201 or consent of instructor. The theory behind practical nuclear magnetic resonance spectroscopy and a survey.
Chemistry 266   Mass Spectrometry. (1) Three hours of lecture per week for five weeks. Prerequisite: 200 or 201 or consent of instructor. Basic mass spectrometric ionization techniques and analyzers as well as simple fragmentation mechanisms for organic molecules; methods for analyzing organic and inorganic samples, along with an opportunity to be trained and checked out on several open-access mass spectrometers; in-depth instruction on the use of mass spectrometry for the analysis of biomolecules such as proteins, peptides, carbohydrates, and nucleic acids.
Chemistry 267   Organic Specialties. (1) Three hours of lecture per week for five weeks. Prerequisite: Graduate-level understanding of organic synthesis or consent of instructor. A survey course focusing on an area of organic chemistry of importance, such as pharmaceutical chemistry, combinatorial chemistry, natural products chemistry, etc.
Chemistry 268   Mass Spectrometry. (2) Course 266 will restrict credit if completed before 268. Three hours of lecture per week for 10 weeks. Prerequisite: Graduate standing or consent of instructor. Principles, instrumentation, and applications in mass spectrometry, including ionization methods, mass analyzers, spectral interpretation, multidimensional methods (GC/MS, HPLC/MS, MS/MS), with emphasis on small organic molecules and bioanalytical applications (proteins, peptides, nucleic acids, carbohydrates, noncovalent complexes); this
will include the opportunity to be trained and checked out on several open-access mass spectrometers. (S)
Chemistry 270A   Advanced Biophysical Chemistry I. (1) Two hours of lecture per week for seven and one-half weeks. Prerequisite: 200 or consent of instructor. Underlying principles and applications of methods for biophysical analysis of biological macromolecules. (F)
Chemistry 270B   Advanced Biophysical Chemistry II. (1) Two hours of lecture per week for seven and one-half weeks. Prerequisite: 270A or consent of instructor. More applications of methods for biophysical analysis of biological macromolecules. (F)
Chemistry 271A   Chemical Biology I: Structure, Synthesis, and Function of Biomolecules. (1) Three hours of lecture per week for five weeks. Prerequisite: 200 or consent of instructor. This course will present the structure of proteins, nucleic acids, and oligosaccarides from the perspective of organic chemistry. Modern methods for the synthesis and purification of these molecules will also be presented. (S)
Chemistry 271B   Chemical Biology II: Enzyme Reaction Mechanisms. (1) Three hours of lecture per week for five weeks. Prerequisite: 271A or consent of instructor. The course will focus on the principles of enzyme catalysis. The course will begin with an introduction to the general concepts of enzyme catalysis, which will be followed by detailed examples that will examine the chemistry behind the reactions and the three-dimensional structures that carry out the transformations. (S)
Chemistry 271C   Chemical Biology III: Contemporary Topics in Chemical Biology. (1) Three hours of lecture per week for five weeks. Prerequisite: 271B or consent of instructor. This course will build on the principles discussed in Chemical Biology I and II. The focus will consist of case studies where rigorous chemical approaches have been brought to bear on biological questions. Potential subject areas will include signal transduction, photosynthesis, immunology, virology, and cancer. For each topic, the appropriate bioanalytical techniques will be emphasized. (S)
Chemistry 272A   Bio X-ray I. (1) Three hours of lecture per week for five weeks. Prerequisite: 270A- 270B or consent of instructor. Theory and application of X-ray crystallography to biomacromolecules.
(S)
Chemistry 272B   Bio X-Ray II. (1) Three hours of lecture per week for five weeks. Prerequisite: 272A or consent of instructor. More sophisticated aspects of the application of X-ray crystallography to biomacromolecules. (S)
Chemistry 273A   Bio NMR I. (1) Two hours of lecture per week for seven and one-half weeks. Prerequisites: 270A-270B or consent of instructor. Fundamentals of multidimensional NMR spectroscopy (including use of the density matrix for analysis of spin response to pulse sequences) and applications of multidimensional NMR in probing structure, interactions, and dynamics of biological molecules will be described.
Chemistry 273B   Bio NMR II. (1) Two hours of lecture per week for seven and one-half weeks. Prerequisite: 273A. Triple resonance methods for determination of protein and nucleic acid resonance assignments, and for generation of structural restraints (distances, angles, H-bonds, etc.). Methods for calculating biomolecular structures from NMR data and the quality of such structures will be discussed.
Chemistry 295   Special Topics. (1-3) Course may be repeated for credit. Must be taken on a satisfactory/
unsatisfactory basis. Prerequisite: Graduate standing or consent of instructor. Lecture series on topics of current interest. Recently offered topics: Natural products synthesis, molecular dynamics, statistical mechanics, molecular spectroscopy, structural biophysics, organic polymers, electronic structure of molecules, and bio-organic chemistry. (F, S)
Chemistry 298   Seminars for Graduate Students. (1-3) Course may be repeated for credit. Must be taken
on a satisfactory/unsatisfactory basis. Seminars. Prerequisite: Graduate standing. In addition to the weekly Graduate Research Conference and weekly seminars on topics of interest in biophysical, organic, physical, nuclear, and inorganic chemistry, there are group seminars on specific fields of research. Seminars will be announced at the beginning of each semester. (F, S)
Chemistry 299   Research for Graduate Students. (1-9) Course may be repeated for credit. Laboratory. Prerequisite: Graduate standing. The facilities of the laboratory are available at all times to
graduate students pursuing original investigations toward an advanced degree at this
University. Such work is ordinarily in collaboration with members of the staff. (F, S)
Chemistry 602   Individual Study for Doctoral Students. (1-8) Course may be repeated for credit.
Must be taken on a satisfactory/unsatisfactory basis. Individual study in consultation with the major field adviser, intended to provide an opportunity for qualified students to prepare
themselves for the various examinations required of candidates for the Ph.D. degree. May not be used for unit or residence requirements for the doctoral degree. (F, S)
Professional Courses
 
Class Description
Chemistry 300   Professional Preparation: Supervised Teaching of Chemistry. (2) Course may be
repeated for credit. Prerequisites: Graduate standing and appointment as a graduate
student instructor. Discussion, curriculum development, class observation, and practice
teaching in chemistry. (F, S)
Chemistry 301A   Undergraduate Laboratory Instruction. (2) Course may be repeated once for credit. Must be taken on a passed/not passed basis. One hour of lecture, four hours of tutoring during 1A-1B laboratories, and one office hour per week. Prerequisites: Junior standing or instructor approval; completion of 1A-1B with a grade of B- or better. Tutoring of students in 1A-1B laboratories. Students attend one hour of the regular GSI preparatory meeting and hold one office hour per week to answer questions about laboratory assignments. (F, S)
Chemistry 301B   Undergraduate Chemistry Instruction. (2) Formerly 301. Course may be repeated once for credit. Must be taken on a passed/not passed basis. One hour of lecture and five hours of tutoring per week. Prerequisites: Sophomore standing; completion of 1A-1B with grade of B- or better. Tutoring of students in 1A-1B. Students attend a weekly meeting on tutoring methods at the Student Learning Center and attend 1A-1B lectures. (F, S)
Chemistry 301C   Chemistry 3 Laboratory Assistant. (2) Course may be repeated once for credit. Must
be taken on a passed/not passed basis. One hour of preparation meeting, four hours of
instruction in the laboratory, and one hour of laboratory experiment preparation per week.
Prerequisites: Sophomore standing and consent of instructor; completion of Chemistry
3B with a grade of B or better. Undergraduate organic laboratory assistants help in the teaching of the Chemistry 3A-3B laboratories. Each week students attend a laboratory preparation meeting for one hour, assist in the laboratory section for four hours, and help in the development of experiments for one hour. (F, S)
Chemistry 301T   Undergraduate Preparation for Teaching or Instruction in Teaching. (2) Course may be repeated for a maximum of 8 units. Two or three hours of lecture and one hour of teacher training per week. Prerequisites: Junior standing, overall GPA of 3.1, and consent of instructor. (F, S)
Chemistry 301W   Supervised Instruction of Chemistry Scholars. (2) Course may be repeated for credit. Must be taken on a passed/not passed basis. One hour of lecture and three or four hours of tutoring per week. Prerequisites: Sophomore standing and consent of instructor. Tutoring of students in the College of Chemistry Scholars Program who are enrolled in general or organic chemistry. Students attend a weekly meeting with instructors.
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